An Overview of the Identification, Prevention, and Management of Immunological Reactions to Blood Transfusion

lood transfusions are prevalent treatment procedures nowadays for various medical conditions that involve the administration of whole blood or separated components alone in combinations can be administered intravenously; these undertaken with therapeutic curative goals mind, they may carry associated risks and complications must weighed against benefits before initiating therapy. A typical subset includes Transfusion reactions. These include Non-infectious (Acute Delayed) infectious complications. transfusion reactions Immune-mediated to components, such as Febrile Non-hemolytic (FNHTR), Allergic reactions, Hemolytic (HTR), Transfusion-related Acute Lung Injury (TRALI), Associated Graft versus Host Disease (TAGVHD), have different mechanism between them. They differentiated action, presentation time, clinic. Blood immunological remain a significant concern clinical settings, leading symptoms. Diagnosing requires careful monitoring evaluation patient’s status laboratory parameters. The prevention methods pre-transfusion testing, selecting appropriate products, using leukoreduced products. Treatment options supportive care, discontinuation transfusion, immunosuppressive therapy severe cases. This article aims provide an overview how identify immune-mediated manage them occur, even prevent if possible.